期刊
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
卷 263, 期 3, 页码 126-130出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s004040050010
关键词
disseminated intravascular coagulopathy pregnancy; abruptio placenta; intrauterine fetal demise; amniotic fluid embolism
In pregnancy and puerperium disseminated intravascular coagulopathy may accompany abruptio placenta, intrauterine fetal demise with retained dead fetus, amniotic fluid embolism, endotoxin sepsis, preecalampsia with HELLP and massive transfusion. Clinical signs and symptoms of DIC can include oozing from venupuncture sites and/or mucous membranes, red cell lysis from activation of the complement system, hemorrhage from coagulopathy and possible uterine atony, hypotension from hemorrhage and/or bradykinin release, and oliguria from end-organ insult and hypovolemia/hypotension. Treatment of DIC consists of replacement of volume, blood products, and coagulation components and cardiovascular and respiratory support with elimination of underlying triggering mechanism.
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