期刊
CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 10, 期 1, 页码 34-39出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-440X(99)00045-7
关键词
-
Recent studies have led to increased appreciation of the influence of excluded volume in solutions of high total macromolecular content ('macromolecular crowding') upon the various classes of reaction that lead to the assembly of proteins and protein complexes. In general, crowding is expected to stabilize native protein structure relative to less compact non-native structures and to favor the formation of functional complexes of native proteins. Under certain pathological conditions, 'overcrowding' may enhance the formation of nonfunctional aggregates of non-native protein (e.g, amyloid and inclusion bodies).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据