期刊
MICRON
卷 31, 期 1, 页码 97-111出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0968-4328(99)00065-7
关键词
electron microscopy; electron microscope tomography; high-resolution scanning electron microscopy; light microscopy; mitochondria; mitochondrial structure
类别
资金
- NCRR NIH HHS [RR04050] Funding Source: Medline
Novel applications of microscopy have recently provided new insights into mitochondrial structures, Diverse techniques such as high resolution scanning electron microscopy, transmission electron microscopy, electron microscope tomography and light microscopy have contributed a better understanding of mitochondrial compartmentalization, dynamic networks of mitochondria, intermembrane bridges, segregation of mitochondrial DNA and contacts with the endoplasmic reticulum among other aspects. This review focuses on advances reported in the last five years concerning aspects of mitochondrial substructure or dynamics gained through new techniques, whether they be novel microscope methods or new ways to prepare or label specimens. Sometimes these advances have produced surprising results and more often than not, they have challenged current conceptions of how mitochondria work. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
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