期刊
BIOMEDICINE & PHARMACOTHERAPY
卷 67, 期 3, 页码 215-217出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2010.12.010
关键词
Chalcone; Pyrimidine; Synthesis; Antitumor activity
资金
- National Natural Science Foundation of China [20772042]
A novel series of chalcone derivatives containing pyrimidinyl group were synthesized and evaluated for their cytotoxic activities in vitro against various human cancer cell lines. Most of the prepared compounds showed potential cytotoxicity against several human cancer cell lines. The compound 5g displayed more potent cytotoxic activities against human cancer cell lines in comparison with Curcumin. (C) 2013 Published by Elsevier Masson SAS.
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