期刊
BIOMEDICAL RESEARCH-TOKYO
卷 30, 期 1, 页码 25-29出版社
BIOMEDICAL RESEARCH PRESS LTD
DOI: 10.2220/biomedres.30.25
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Normal rats were given catechin-rich green tea as drinking fluid and the effects on hepatic gene expression were examined. The results of DNA microarray analysis and quantitative real-time reverse transcription-polymerase chain reaction indicated the down-regulated expression of genes for glucose-6-phosphatase (G6Pase) and fatty acid synthase, and the up-regulated expression of peroxisome proliferator activated receptor cc in the rats given green tea for 4 weeks as compared with the water-given animals. One may expect anti-diabetic activity by catechin-rich green tea through its chronic down-regulatory effect on G6Pase expression.
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