期刊
BIOMEDICAL MATERIALS
卷 7, 期 1, 页码 -出版社
IOP Publishing Ltd
DOI: 10.1088/1748-6041/7/1/015006
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Transparent poly(vinyl alcohol) (PVA) hydrogel films, derived from aqueous solutions of varying concentration, were synthesized by the cyclic freeze-thaw method (0 degrees -37 degrees C). This study demonstrates a variation in the transparency, degree of crystallinity, wettability, swelling and mechanical properties of the hydrogels as a function of the solution concentration and the number of freeze-thaw cycles for a given average molecular weight (95 000 Da). The study manifests a strong control of the number of freeze-thaw cycles on the structure-property correlations of the synthesized transparent PVA hydrogels, revealing the possibility of obtaining a window of structural and process parameters for the physically cross-linked hydrogels, making them suitable for cell-gel interactions.
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