期刊
JOURNAL OF CELL BIOLOGY
卷 212, 期 1, 页码 9-11出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201512032
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- NIAMS NIH HHS [R01 AR069078] Funding Source: Medline
Epigenetic regulators are essential for cell lineage choices during development. In this issue, Mardaryev et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506065) show that Polycomb subunit Cbx4 acts downstream of transcriptional regulator p63 to maintain epidermal progenitor identity and proliferation in the developing epidermis via Polycomb-dependent and -independent SUMO E3 ligase activities.
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