期刊
BIOTECHNOLOGY LETTERS
卷 22, 期 5, 页码 341-346出版社
KLUWER ACADEMIC PUBL
DOI: 10.1023/A:1005612415737
关键词
fed-batch culture; glycerol; methanol; mixed substrates; Pichia pastoris
A simple, accurate model capable of predicting cell growth and methanol utilization during the mixed substrate fed-batch fermentation of Mut(S) recombinant Pichia pastoris was developed and was used to design an exponential feeding strategy for mixed substrate fed-batch fermentation at a constant specific growth rate. Mixed substrate feeding has been shown to boost productivity in recombinant fed-batch culture of P. pastoris, while fixed growth rate exponential feeding during fed-batch culture is a useful tool in process optimization and control.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据