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The diagnostic evaluation, treatment. and prevention of allergic contact dermatitis in the new millennium

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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
卷 105, 期 3, 页码 409-420

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MOSBY-ELSEVIER
DOI: 10.1067/mai.2000.104937

关键词

allergic contact dermatitis; common allergens; clinical manifestations; diagnostic evaluation; immunoregulation; treatment; prevention

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Identifying the etiology of allergic contact dermatitis is a rewarding yet challenging endeavor. Not all allergic contact reactions are eczematous in appearance. The most reliable clinical clue to the allergic nature of the dermatitis is its geographic distribution. Once a list of culprit allergens has been identified by patch testing, the practitioner must identify the relevant allergen(s) and counsel the patient in avoidance. For most individuals, allergen avoidance results in resolution of the dermatitis; however, some patients will require continuing symptomatic therapy despite avoidance. For those patients unable to avoid known allergens, immunosuppressant therapies (including phototherapy) or barriers ran be beneficial. Currently, hyposensitization is not a viable alternative for the treatment of allergic contact dermatitis.

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