期刊
INTERNATIONAL JOURNAL OF PHARMACEUTICS
卷 196, 期 2, 页码 155-159出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0378-5173(99)00411-1
关键词
drugs; nanoparticles; polydispersity index
The major problem of many newly developed pharmaceutical drugs is their poor solubility in water and simultaneously in organic media. To solve these problems formulation as nanosuspensions is an attractive alternative. During the drug development process screening for an optimal formulation by homogenisation is essential. Time and cost effective production in an initial phase of R&D can be conducted on lab scale by using the Micron Lab 40 in its discontinuous version. In this report reproducibility of small scale production parameters (particle size, size distribution, content of microparticles) was exemplary studied for the drug RMKP22. (C) 2000 Elsevier Science B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据