期刊
CURRENT OPINION IN CELL BIOLOGY
卷 12, 期 2, 页码 217-221出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(99)00085-X
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- NIDDK NIH HHS [DK54441] Funding Source: Medline
Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger mediated signaling events. Localization of the cAMP-dependent protein kinase (PKA) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs). In the past year there have been many advances in our understanding of AKAPs, particularly in the field of the functional consequences of PKA anchoring.
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