期刊
BIOMATERIALS
卷 33, 期 1, 页码 189-206出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biomaterials.2011.09.032
关键词
Nanoprobes; In vitro diagnostics; Molecular identification; Protein detection; Cancer; Infectious diseases
资金
- National Natural Science Foundation of China [21021061, 81000662]
- Fundamental Research Funds for the Central Universities [2010121012]
- Research Funds for the Doctoral Program of Higher Education of China [20100121120009]
- Program for New Century Excellent Talents in University [NCET-10-0709]
- China Postdoctoral Science Foundation [20110490849]
The successful and explosive development of nanotechnology is significantly impacting the fields of biology and medicine. Among the spectacular developments of nanobiotechnology, interest has grown in the use of nanomaterials as nanoprobes for bioanalysis and diagnosis. Herein, we review state-of-the-art nanomaterial-based probes and discuss their applications in in vitro diagnostics (IVD) and challenges in bringing these fields together. Major classes of nanoprobes include quantum dots (QDs), plasmonic nanoparticles, magnetic nanoparticles, nanotubes, nanowires, and multifunctional nanomaterials. With the advantages of high volume/surface ratio, surface tailorability, multifunctionality, and intrinsic properties, nanoprobes have tremendous applications in the areas of biomarker discovery, diagnostics of infectious diseases, and cancer detection. The distinguishing features of nanoprobes for in vitro use, such as harmlessness, ultrasensitivity, multiplicity, and point-of-care use, will bring a bright future of nanodiagnosis. (C) 2011 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据