期刊
CURRENT OPINION IN MICROBIOLOGY
卷 3, 期 2, 页码 159-164出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S1369-5274(00)00069-2
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Conventional antisense RNAs, such as those controlling plasmid replication and maintenance, inhibit the function of their target RNAs rapidly and efficiently Novel findings show that a common Ii-turn loop structure mediates fast RNA pairing in the majority of these RNA controlled systems. Usually, an antisense RNA regulates a single, cognate target RNA only. Recent reports, however, show that antisense RNAs can act as promiscuous regulators that control multiple genes in concert to integrate complex physiological responses in Escherichia coli.
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