期刊
CHEST
卷 117, 期 4, 页码 1065-1072出版社
AMER COLL CHEST PHYSICIANS
DOI: 10.1378/chest.117.4.1065
关键词
closing pressure; mandibular position; obstructive sleep apnea; oral appliance; pharynx
Study objectives: To examine dose-dependent effects of mandibular advancement on collapsibility of the passive pharynx and sleep-disordered breathing (SDB), Design: Prospective, randomized study. Setting: University hospital. Patients: Thirty-seven adult patients with SDB, Interventions: Oral appliances with 2-, 4-, and 6-mm advancement of the mandible, Measurements and results: Overnight oximetry was performed with and without oral appliances, Each 2-mm mandibular advancement coincided with approximately 20% improvement in number and severity of nocturnal desaturations. Percentages of patients producing a > 50% improvement rate of the number of desaturations were 25%, 48%, and 65% with use of oral appliances with 2-, 4-, and Ci-mm mandibular advancement, respectively. Static pharyngeal mechanics mere evaluated in six completely paralyzed patients with SDB under general anesthesia with and without the oral appliances, Advancement of mandibular position,vas found to produce dose-dependent closing pressure reduction of all pharyngeal segments, Normalization of nocturnal oxygenation was associated with negative closing pressure, especially at the velopharynx. Conclusions: We: conclude that improvement of both nocturnal oxygenation and pharyngeal collapsibility significantly depends on the mandibular position.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据