期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 25, 期 4, 页码 165-173出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(00)01559-0
关键词
-
资金
- NCI NIH HHS [CA60836] Funding Source: Medline
- NIGMS NIH HHS [GM34622] Funding Source: Medline
Studies in the 1960s implied that bacteriophage T4 tightly couples DNA replication to genetic recombination, This contradicted the prevailing wisdom of the time, which staunchly supported recombination as a simple cut-and-paste process. More-recent investigations have shown how recombination triggers DNA synthesis and why the coupling of these two processes is important. Results from T4 were instrumental in our understanding of many important replication and recombination proteins, including the newly recognized replication/recombination mediator proteins. Recombination-dependent DNA replication is crucial to the T4 life cycle as it is the major mode of DNA replication and is also central to the repair of DNA breaks and other damage.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据