期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 10, 期 8, 页码 835-838出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(00)00110-4
关键词
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A series of 8-alkylamino-5,7-dihydroxyflavones was prepared from chrysine via a seven step sequence. The synthesis of their B-alkylamino isomers could be subsequently accomplished through a convenient extension of the Wessely-Moser rearrangement. These compounds were found to be efficient neuroprotective agents in vitro. (C) 2000 Elsevier Science Ltd. All rights reserved.
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