期刊
BIOMARKERS
卷 19, 期 6, 页码 437-443出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/1354750X.2014.923048
关键词
Bile duct cancer; biomarker; cholangiocarcinoma; diagnosis; prognosis; serum
Context: Bile duct cancer (BDC) is a disease with a very grave prognosis, often diagnosed too late. Objective: The aim of this review is to evaluate available literature on tumor markers in serum from patients with BDC. Methods: Using the search words serum markers'', bile duct cancer'', cholangiocarcinoma'', biomarker'' and tumor marker'', a search was carried out. Results: Seventy-five studies were included in the review. Conclusion: CA19-9 is by far the most studied and most promising diagnostic and/or prognostic marker in BDC. But also the different mucins are interesting as new markers of BDC in serum.
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