期刊
BIOMARKERS
卷 18, 期 1, 页码 10-22出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/1354750X.2012.719035
关键词
alpha 1-acid glycoprotein; fibronectin; glycodelin-S; glycome; prostate-specific antigen
资金
- Pbmn 81 Wroclaw Medical University
Context: Disturbed protein-carbohydrate interactions may underlie the molecular mechanism of some diseases of the male reproductive tract, including infertility and prostate diseases. Objective: To summarize the current knowledge on the glycosylation patterns of glycodelin-S, fibronectin, prostate-specific antigen, and alpha(1)-acid glycoprotein. Results: Some rare glycoepitopes have been found in seminal plasma glycoproteins: high-mannose and polylactosamine-type glycans, and N-glycans containing N-acetyl-galactosamine. The glycosylation profiles occur altered in pathological conditions. Conclusion: Further detailed studies may lead up to indicate the biomarkers useful in the management of male reproductive tract disorders.
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