期刊
BIOMARKERS
卷 15, 期 3, 页码 249-258出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/13547500903502802
关键词
Exercise; alpha 1-antichymotrypsin; C-1 protease inhibitor; proteomics
资金
- NCRR NIH HHS [5M01 RR00425] Funding Source: Medline
Proteomics was utilized to identify novel potential plasma biomarkers of exercise-induced muscle injury. Muscle injury was induced in nine human volunteers by eccentric upper extremity exercise. Liquid chromatography-mass spectrometry identified 30 peptides derived from nine proteins which showed significant change in abundance post-exercise. Four of these proteins, haemoglobin alpha chain, haemoglobin beta chain, alpha 1-antichymotrypsin (ACT) and plasma C-1 protease inhibitor (C1 Inh), met the criterion for inclusion based on changes in at least two distinct peptides. ACT and C1 Inh peptides peaked earlier post-exercise than creatine kinase, and thus appear to provide new information on muscle response to injury.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据