期刊
BRITISH JOURNAL OF HAEMATOLOGY
卷 109, 期 2, 页码 459-462出版社
BLACKWELL SCIENCE LTD
DOI: 10.1046/j.1365-2141.2000.01977.x
关键词
myelofibrosis; children; prognosis
类别
Idiopathic myelofibrosis can develop in children as well as adults, However, the disease appears to be much more aggressive in adults, being characterized by poor survival rates and a high frequency of malignant transformation, Here, We describe three cases of idiopathic myelofibrosis in infants, two of whom were followed for 16 and 22 years after diagnosis, Neither of these patients required more than minimal supportive care, and both have had spontaneous erythropoietic recovery as early as 2-3 years after diagnosis. There have been no indications of malignant transformation or clinical deterioration. Thus, idiopathic myelofibrosis may have a different pathogenesis and clinical course in infants from adults, requiring a more conservative approach to management.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据