期刊
BIOMACROMOLECULES
卷 13, 期 8, 页码 2333-2338出版社
AMER CHEMICAL SOC
DOI: 10.1021/bm300578p
关键词
-
资金
- NIH [CA112085, GM60938]
- W.M. Keck Foundation
- Skaggs Institute for Chemical Biology
Virus-like particles (VLPs) have proven to be versatile platforms for chemical and genetic functionalization for a variety of purposes in biomedicine, catalysis, and materials science. We describe here the simultaneous modification of the bacteriophage Q beta VLP with a metalloporphyrin derivative for photodynamic therapy and a glycan ligand for specific targeting of cells bearing the CD22 receptor. This application benefits from the presence of the targeting function and the delivery of a high local concentration of singlet Oxygen-generating payload.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据