期刊
INFECTION AND IMMUNITY
卷 68, 期 5, 页码 3034-3035出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.68.5.3034-3035.2000
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资金
- NCI NIH HHS [P30 CA034196] Funding Source: Medline
- NIAID NIH HHS [AI30389, AI 39705, AI42362] Funding Source: Medline
We have investigated the roles of gamma interferon (IFN-gamma) and interleukin-1 (IL-4) in host defense against Brugia malayi. Our data suggest that the lack of either IFN-gamma or IL-4 prolongs the time required to achieve sterile immunity, suggesting that bath canonical type 1 and type 2 responses are involved in the clearance of infection.
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