期刊
BIOPHYSICAL JOURNAL
卷 78, 期 5, 页码 2675-2679出版社
BIOPHYSICAL SOCIETY
DOI: 10.1016/S0006-3495(00)76811-1
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We have developed a hybrid scanning ion conductance and scanning near-field optical microscope for the study of living cells. The technique allows quantitative, high-resolution characterization of the cell surface and the simultaneous recording of topographic and optical images. A particular feature of the method is a reliable mechanism to control the distance between the probe and the sample in physiological buffer. We demonstrate this new method by recording near-field images of living cells (cardiac myocytes).
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