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DMRT1 prevents female reprogramming in the postnatal mammalian testis
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Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development
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Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8
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SERKAL syndrome: An autosomal-recessive disorder caused by a loss-of-function mutation in WNT4
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Wt1 negatively regulates β-catenin signaling during testis development
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Sox8 is a critical regulator of adult Sertoli cell function and male fertility
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Stabilization of β-catenin in XY gonads causes male-to-female sex-reversal
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HUMAN MOLECULAR GENETICS (2008)
Activation of β-catenin signaling by Rspo1 controls differentiation of the mammalian ovary
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L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer
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MOLECULAR AND CELLULAR BIOLOGY (2008)
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
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A comprehensive survey of the laminins and collagens type IV expressed in mouse Leydig cells and their regulation by LH/hCG
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Peritubular myoid cells are not the migrating population required for testis cord formation in the XY gonad
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Loss of Wnt4 and Foxl2 leads to female-to-male sex reversal extending to germ cells
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HUMAN MOLECULAR GENETICS (2007)
Sex-specific differences in mouse DMRT1 expression are both cell type- and stage-dependent during gonad development
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SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells
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AMERICAN JOURNAL OF PATHOLOGY (2007)
Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development
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R-spondin1 is essential in sex determination, skin differentiation and malignancy
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The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis
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Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence
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DEVELOPMENT (2006)
Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination
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PLOS BIOLOGY (2006)
Evaluation of candidate markers for the peritubular myoid cell lineage in the developing mouse testis
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Role of the basic helix-loop-helix transcription factor, scleraxis, in the regulation of sertoli cell function and differentiation
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Foxl2 is required for commitment to ovary differentiation
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Functional analysis of Sox8 and Sox9 during sex determination in the mouse
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DEVELOPMENT (2004)
One tissue, two fates: Molecular genetic events that underlie testis versus ovary development
J Brennan et al.
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SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors
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DEVELOPMENTAL BIOLOGY (2004)
Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy
CC Stolt et al.
DEVELOPMENT (2004)
Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad
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DEVELOPMENT (2003)
Type II and type IX collagen transcript isoforms are expressed during mouse testis development
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Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice
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Conditional inactivation of Sox9:: A mouse model for campomelic dysplasia
R Kist et al.
GENESIS (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
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METHODS (2001)
Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8
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MOLECULAR AND CELLULAR BIOLOGY (2001)
Spectrum of FOXL2 gene mutations in blepharophimosis-ptosis-epicanthus inversus (BPES) families demonstrates a genotype-phenotype correlation
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Sox9 induces testis development in XX transgenic mice
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Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
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The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome
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The transcription factor Sox10 is a key regulator of peripheral glial development
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A transgenic insertion upstream of Sox9 is associated with dominant XX sex reversal in the mouse
CE Bishop et al.
NATURE GENETICS (2000)
Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
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GENES & DEVELOPMENT (2000)
The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences
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NUCLEIC ACIDS RESEARCH (2000)
SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
SRY, SOX9, and DAX1 expression patterns during human sex determination and gonadal development
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