期刊
MICROBES AND INFECTION
卷 2, 期 6, 页码 643-649出版社
ELSEVIER
DOI: 10.1016/S1286-4579(00)00361-0
关键词
Entamoeba histolytica; pathogenesis; lectin; cell adhesion; cell movement
The human pathogenic protozoan Entamoeba histolytica is a motile cell polarized into a front pseudopod and a rear uroid. The amoebic Gal/GalNAc surface lectin is a major adhesion molecule composed of an immunodominant 170-kDa heavy subunit, mostly extracellular except for a short cytoplasmic tail, and of an extracellular light subunit. The binding of multivalent ligands triggers lectin capping and recruitment to the uroid. The properties of the Gal/GalNAc lectin and its role in amoeba adhesion and uroid polarization are reviewed in the context of the molecular mechanisms underlying cell polarization and locomotion. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据