期刊
TETRAHEDRON LETTERS
卷 41, 期 21, 页码 4069-4073出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(00)00592-X
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Application of a carbon-carbon bond forming reaction for ligating unprotected peptides in acetic acid is described based on a Pictet-Spengler condensation. The peptide segments include a peptide with a Trp at the N-terminal and another with a C-terminal aldehyde, which can be generated through a new cyclic acetal resin. (C) 2000 Elsevier Science Ltd. All rights reserved.
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