期刊
CIRCULATION
卷 101, 期 21, 页码 2503-2509出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/01.CIR.101.21.2503
关键词
atherosclerosis; magnetic resonance imaging; aorta; echocardiography; plaque
资金
- NHLBI NIH HHS [R01HL61801, P50HL54469] Funding Source: Medline
Background-The structure and composition of aortic atherosclerotic plaques are associated with the risk of future cardiovascular events. Magnetic resonance (MR) imaging may allow accurate visualization and characterization of aortic plaques. Methods and Results-We developed a noninvasive MR method, free of motion and blood flow artifacts, for submillimeter imaging of the thoracic aortic wall. MR imaging was performed on a clinical MR system in 10 patients with aortic plaques identified by transesophageal echocardiography (TEE), Plaque composition, extent, and size were assessed from T1-, proton density-, and T2-weighted images. Comparison of 25 matched MR and TEE cross-sectional aortic plaque images showed a strong correlation for plaque composition (chi(2)=43.5, P<0.0001; 80% overall agreement; n=25) and mean maximum plaque thickness (r=0.88, n=25; 4.56+/-0.21 mm by MR and 4.62+/-0.31 mm by TEE). Overall aortic plaque extent as assessed by TEE and MR was also statistically significant (chi(2)=61.77, P<0.0001; 80% overall agreement; n=30 regions). Conclusions-This study demonstrates that noninvasive MR evaluation of the aorta compares well with TEE imaging for the assessment of atherosclerotic plaque thickness, extent, and composition. This MR method may prove useful for the in vivo study of aortic atherosclerosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据