期刊
CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 10, 期 3, 页码 279-285出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-440X(00)00085-3
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During the past decade, physical techniques such as optical tweezers and atomic force microscopy were used to study the mechanical properties of DNA at the single-molecule level. Knowledge of DNA's stretching and twisting properties now permits these single-molecule techniques to be used in the study of biological processes such as DNA replication and transcription.
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