期刊
CURRENT BIOLOGY
卷 10, 期 11, 页码 667-670出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0960-9822(00)00517-0
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In the fruit fly Drosophila melanogaster, locomotor activity is sexually dimorphic: female flies constantly modulate their activity pattern whereas males show a steadier, stereotyped walking pace [1]. Here, we mapped the area of the brain controlling this behavioural dimorphism. Adult male Drosophila expressing a dominant feminising transgene in a small cluster of neurons in the pars intercerebralis exhibited a female-like pattern of locomotor activity. Genetic ablation of these neurons prevented the feminisation of the locomotor activity of transgenic males, The results suggest that this cluster of neurons modulates sex-specific activity, but is not involved in initiating fly locomotion, Nor does it control male courtship behaviour, because feminisation of courtship was not correlated with the feminisation of locomotor activity.
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