期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 129, 期 6, 页码 544-546出版社
CONSULTANTS BUREAU
DOI: 10.1007/BF02434871
关键词
dimebon; H-1 receptor inhibitor; tacrine; AF64A; avoidance conditioning; rats
Systemic administration of antihistamine drug dimebon improves active avoidance conditioning in rats with chronic partial deprivation of cerebral cholinergic functions caused by intracerebroventricular injections of AF64A. The effects of dimebon on learning are similar to those of tacrine used in the treatment of Alzheimer's disease.
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