期刊
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
卷 13, 期 2, 页码 151-162出版社
ELSEVIER SCI LTD
DOI: 10.1053/beha.1999.0065
关键词
anaemia; infection; cytokines; ferrokinetics; erythropoietin; iron; host defence
类别
资金
- NHLBI NIH HHS [HL53703] Funding Source: Medline
Anaemia is a common finding in infected individuals, and in many cases is an indicator of disease activity and/or duration. The term 'anaemia of infection' refers to a specific syndrome related to the more broadly defined 'anaemia of chronic disease', in this syndrome, cytokines produced as part of the host response to infection induce anaemia by well-defined pathophysiological mechanisms. In this chapter, the diagnosis, significance, pathophysiology and treatment of the anaemia of infection will be reviewed. Other mechanisms which can produce anaemia in infected individuals will also be reviewed.
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