期刊
SURFACE & COATINGS TECHNOLOGY
卷 128, 期 -, 页码 313-319出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/S0257-8972(00)00593-4
关键词
biomaterials; titanium; apatite; surface coating; ion implantation
CaO and P2O5-containing Ti surfaces were prepared and examined for their bioactivity. The preparation involved the incorporation of Ca and P into Ti by ion implantation to a total dose of up to 8 x 10(17) ions/cm(2) with a 1.7 Ca/P ratio and a subsequent oxidation at 500 degrees C in O-2 for 30 min. The model surfaces were examined for their reactivity toward hydroxyapatite formation by microscopically recording the mineralization in a simulated body fluid. The ion implantation-modified surfaces were shown to exhibit enhanced mineralization by inducing heterogeneous nucleation, growth, and proliferation of hydroxyapatite, relative to a control sample of pure Ti. The surface-induced reactivity was shown to relate to the enhanced provision of the ionic mineral components Ca2+ and HPO42- directly supplied from the surface and the substrate-mediated nucleation by the hydroxylated surface of TiO2. (C) 2000 Elsevier Science S.A. All rights reserved.
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