期刊
NETHERLANDS JOURNAL OF MEDICINE
卷 56, 期 6, 页码 211-214出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0300-2977(00)00019-X
关键词
septic shock; critical illness polyneuropathy; multi organ dysfunction syndrome
Background: To estimate the incidence and onset of critical illness polyneuropathy (CIP) in patients in septic shock. Methods: Prospective, observational study, no interventions, in a general 9-bed ICU of a large teaching hospital. Twenty-five patients consecutively admitted to the ICU for treatment of septic shock were studied. Within 72 h of admission to the ICU a complete neurological examination and electromyografic studies were done. Studies were repeated weekly until discharge of ICU or death or CIP confirmed. Results: Nineteen patients developed CIP (76%), with a majority (80%) within 72 h after onset of septic shock. All twenty-two patients with multi organ dysfunction syndrome (MODS) had CIP. The three patients without MODS did not have CIP (P < 0.01). Conclusions: In a group of patients suffering from septic shock the incidence of CIP is high (76%). The onset is early, within 72 h after onset of septic shock. CIP is an early feature of MODS, developing after septic shock. (C) 2000 Elsevier Science B.V. All rights reserved.
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