期刊
CURRENT OPINION IN IMMUNOLOGY
卷 12, 期 3, 页码 323-329出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0952-7915(00)00094-7
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Recent advances in our understanding of cytolytic effector mechanisms include the partial characterization of caspase-independent apoptotic pathways triggered by granzymes, a realization of the vital importance of perforin and granzymes in the defence against certain virus infections in vivo and the first description of hereditary immunodeficiency due to disordered perforin expression in humans.
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