期刊
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
卷 15, 期 11, 页码 1465-1474出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.bbmt.2009.07.019
关键词
Hematopoeitic stem cell transplantation; Infertility; Premature ovarian failure; Information provision; Questionnarie survey
Hematopoietic stem-cell transplantation (HSCT) is associated with high rates of gonadal failure, which is distressing for younger patients desiring to start a family. The perceived importance and optimal timing of discussing fertility- and menopause-related information with women undergoing aggressive treatment such as HSCT is not well defined. Questionnaires were sent to 532 patients who underwent HSCT between January 1987 and September 2004 at the ages of 16 to 50 years. The questionnaire assessed demographic data, the need forfertility-and menopause-related information at various times during treatment, and standardized measures of anxiety, quality of life, and menopausal symptoms. The return rate was 40.2%, with 196 patients participating. Of these, 38% reported that they had discussed fertility-related issues with health-care providers since their diagnosis; 54% had discussed menopause-related issues. At the time of diagnosis, participants considered receiving information on fertility and menopause as being of equal importance. However, after HSCT information about menopause was considered more important than information on fertility (P <= .0001). Being <40 years, being childless, desiring to bear children in the future, and having a high score on the State-Trait Anxiety Inventory (STAI) correlated with higher ratings of importance for both fertility- and menopause-related information. Our result suggested that healthcare providers should provide information on fertility and menopause repeatedly throughout the treatment period, and that menopause-related information should be reemphasized after HSCT Such counseling is crucial for patients who are young and childless. Biol Blood Marrow Transplant 15: 1465-1474 (2009) (C) 2009 American Society for Blood and Marrow Transplantation
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据