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The nucleolus: the magician's hat for cell cycle tricks

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CURRENT OPINION IN CELL BIOLOGY
卷 12, 期 3, 页码 372-377

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CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(00)00102-2

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  1. NIGMS NIH HHS [GM 56800] Funding Source: Medline

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The nucleolus, for decades considered a ribosome factory and site for ribosomal RNA synthesis and processing, has recently acquired new fame. Analyses of proteins important for cell-cycle regulation have shown that this organelle is used to sequester proteins, thereby inhibiting their activity.

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