期刊
AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY
卷 70, 期 6, 页码 405-408出版社
BLACKWELL SCIENCE ASIA
DOI: 10.1046/j.1440-1622.2000.01843.x
关键词
complications; morbidity; pituitary adenoma; trans-sphenoidal surgery
类别
Background: All patients who underwent trans-sphenoidal surgery between January 1984 and December 1998 were reviewed to assess morbidity resulting from this operation. Methods: There were 185 operations on 165 patients. The operative approach was sublabial in 80 cases and transnasal in 105. One surgeon (VB) performed the vast majority of operations. Results: Complications included nasal perforation (7.6%), transient diabetes insipidus (4.9%), permanent diabetes insipidus (3.8%), cerebrospinal fluid fistula (4.3%), donor site haematoma (2.2%) and residual tumour haemorrhage (1.6%) causing ophthalmoplegia (1.1%) and loss of vision (1.1%). Other complications included epistaxis (1.1%), meningitis (0.5%) and sinusitus (0.5%). Injury to the anterior superior alveolar nerve also occurred in the sublabial approach in 63% of patients. There were no perioperative deaths. Conclusions: There is a small but significant risk of a number of complications that should be considered for informed consent of this procedure.
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