期刊
GENE
卷 251, 期 1, 页码 45-53出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0378-1119(00)00192-X
关键词
3T3-L1 adipocyte; adipogenesis; adipocyte specific genes; cDNA/EST microarray
Cellular differentiation is a process in which a group of differentiation specific genes is programmatically induced. This gene expression program leads to changes in both cellular morphological and physiological phenotypes. Using an 18,376-member cDNA/EST microarray, we analyzed the difference in gene expression profiles between differentiated 3T3-L1 adipocyte and nondifferentiated 3T3-L1 preadipocyte. From our study a large number of genes and ESTs were identified as differentially induced or suppressed. In this paper we describe the changes of gene expression profile during 3T3-L1 cell differentiation. (C) 2000 Elsevier Science B.V. All rights reserved.
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