期刊
NEUROREPORT
卷 11, 期 9, 页码 1907-1913出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200006260-00021
关键词
electrical stimulation; epilepsy; frontal eye field; man; saccades; smooth eye movements
Electrical cortical stimulation of the human frontal gyri and the precentral gyrus has been shown to induce eye movements and it has classically been assumed that these stimulation-induced eye movements result from electrical interference with the human homologue of the monkey frontal eye field (FEF). However, amplitude of electrical current and induced type of eye movement, which are essential for the determination of eye fields in the monkey, have not been investigated systematically in man. We applied electrical cortical stimulation in the lateral frontal cortex in six epileptic patients. Sites whose stimulation resulted in eye movements were determined with respect to gyral and sulcal patterns, Talairach coordinates and neighboring functions as found by electrical cortical stimulation. Based on this approach, a restricted location of the electrically defined FEF is proposed within a larger oculomotor region on the posterior part of the middle frontal gyrus. NeuroReport 11:1907-1913 (C) 2000 Lippincott Williams & Wilkins.
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