期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 25, 期 7, 页码 307-311出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(00)01588-7
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For many years now, it has been known that Ca2+ is an important signaling molecule in the cytosol of the cell, but emerging evidence suggests that Ca2+ might also play a signaling role in the endoplasmic reticulum. For example, agonist-induced fluctuations in free Ca2+ concentration in the endoplasmic reticulum can affect many functions of the endoplasmic reticulum, including protein synthesis and modification, and interchaperone interactions.
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