Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation - A pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2)

A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs.