期刊
SCIENCE
卷 289, 期 5476, 页码 85-88出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.289.5476.85
关键词
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Domestication of many plants has correlated with dramatic increases in fruit size. In tomato, one quantitative trait Locus (QTL), fw2.2, was responsible for a Large step in this process. When transformed into large-fruited cultivars, a cosmid derived from the fw2.2 region of a small-fruited wild species reduced fruit size by the predicted amount and had the gene action expected for fw2.2. The cause of the QTL effect is a single gene, ORFX, that is expressed early in floral development, controls carpel cell number, and has a sequence suggesting structural similarity to the human oncogene c-H-ras p21. Alterations in fruit size, imparted by fw2.2 alleles, are most Likely due to changes in regulation rather than in the sequence and structure of the encoded protein.
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