期刊
BIOLOGICAL PSYCHIATRY
卷 73, 期 9, 页码 804-810出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.biopsych.2012.08.026
关键词
Addiction; binge eating; dopamine; drug abuse; obesity; opioid
资金
- Cambridge Overseas Trust
- Lilly
- GlaxoSmithKline
- Lundbeck
- Medical Research Council [G00001354]
- Wellcome Trust [G00001354]
- Medical Research Council [G0001354B, G1000183B, G0001354] Funding Source: researchfish
The food addiction model of overeating has been proposed to help explain the widespread advancement of obesity over the last 30 years. Parallels in neural substrates and neurochemistry, as well as corresponding motivational and behavioral traits, are increasingly coming to light; however, there are still key differences between the two disorders that must be acknowledged. We critically examine these common and divergent characteristics using the theoretical framework of prominent drug addiction models, investigating the neurobiological underpinnings of both behaviors in an attempt to justify whether classification of obesity and binge eating as an addictive disorder is merited.
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