期刊
BIOLOGICAL PSYCHIATRY
卷 69, 期 12, 页码 1160-1167出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.biopsych.2011.01.022
关键词
ADHD; attention; cingulate; cognition; decision; frontal; imaging; parietal; reward
资金
- Centers for Disease Control
- National Institutes of Mental Health
- National Science Foundation
- Mental Illness and Neuroscience Discovery (MIND) Institute
- National Alliance for Research on Schizophrenia and Depression (NARSAD)
- Benson-Henry Institute for Mind-Body Medicine at Massachusetts General Hospital
- David Judah Fund
- McIngvale Fund
- Johnson and Johnson Center for the Study of Psychopathology
- Center for Functional Neuroimaging Technologies [P41RR14075]
- McNeil Pharmaceuticals
- Pfizer Pharmaceuticals
- Eli Lilly and Company
Functional and structural neuroimaging have identified abnormalities of the brain that are likely to contribute to the neuropathophysiology of attention-deficit/hyperactivity disorder (ADHD). In particular, hypofunction of the brain regions comprising the cingulo-frontal-parietal cognitive-attention network have been consistently observed across studies. These are major components of neural systems that are relevant to ADHD, including cognitive/attention networks, motor systems, and reward/feedback-based processing systems. Moreover, these areas interact with other brain circuits that have been implicated in ADHD, such as the default mode resting state network. The ADHD imaging data related to cingulo-frontal-parietal network dysfunction will be selectively highlighted here to help facilitate its integration with the other information presented in this special issue. Together, these reviews will help shed light on the neurobiology of ADHD.
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