期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 44, 期 8, 页码 2214-2216出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.44.8.2214-2216.2000
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The patterns of antibiotic resistance in Helicobacter pylori were assessed in two different regions In Japan. Overall, prevalences of resistance to metronidazole and clarithromycin were 12.4 and 12.9%, respectively, While there was no difference in clarithromycin resistance, the prevalence of metronidazole resistance was significantly higher in Kyoto (23.8%) than in Sapporo (8.1%). From 1996 to 1999, the prevalence of metronidazole resistance did not change but the prevalence of clarithromycin resistance doubled (from 9.1 to 18.7%).
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