Coscinamides A, B and C, three new bis indole alkaloids from the marine sponge Coscinoderma sp.

Three novel bis indole alkaloids, coscinamides A-C have been isolated from an extract of the marine sponge Coscinoderma sp., and their structures determined on the basis of spectral data, These compounds contain an unusual alpha-keto enamide functionality and are the first reported alkaloids from this genus, Published by Elsevier Science Ltd.