期刊
BIOLOGICAL CYBERNETICS
卷 103, 期 1, 页码 43-56出版社
SPRINGER
DOI: 10.1007/s00422-010-0384-8
关键词
Latency coding; Channel noise; Fisher information; Morris-Lecar model
资金
- ANR [ANR-09-BLAN-0008-01]
- Ecole Polytechnique
- Agence Nationale de la Recherche (ANR) [ANR-09-BLAN-0008] Funding Source: Agence Nationale de la Recherche (ANR)
The assessment of the variability of neuronal spike timing is fundamental to gain understanding of latency coding. Based on recent mathematical results, we investigate theoretically the impact of channel noise on latency variability. For large numbers of ion channels, we derive the asymptotic distribution of latency, together with an explicit expression for its variance. Consequences in terms of information processing are studied with Fisher information in the Morris-Lecar model. A competition between sensitivity to input and precision is responsible for favoring two distinct regimes of latencies.
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