期刊
EUROPEAN JOURNAL OF CANCER
卷 36, 期 14, 页码 1796-1807出版社
ELSEVIER SCI LTD
DOI: 10.1016/S0959-8049(00)00186-6
关键词
quality of life; head and neck cancer; assessment; questionnaire validation; EORTC QLQ-C30; EORTC QLQ-H&N35
类别
This study tests the reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H&N35) and version 3.0 of the EORTC Core Questionnaire (QLQ-C30) in 622 head and neck cancer patients from 12 countries. The patients completed the QLQ-C30, the QLQ-H&N35 and a debriefing questionnaire before antineoplastic treatment or at a follow-up. 232 patients receiving treatment completed a second questionnaire after treatment. Compliance was high and the questionnaire was well accepted by the patients. Multitrait scaling analysis confirmed the proposed scale structure of the QLQ-H&N35. The QLQ-H&N35 was responsive to differences between disease status, site and patients with different Karnofsky performance status, and to changes over time. The new physical functioning scale (with a four-point response format) of version 3.0 of the QLQ-C30 was shown to be more reliable than previous versions. Thus, the QLQ-H&N35, in conjunction with the VLQ-C30, appears to be reliable, valid and applicable to broad multicultural samples of head and neck cancer patients. (C) 2000 Elsevier Science Ltd. All rights reserved.
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