The direct synthesis of novel enantiomerically pure α-amino acids in protected form via Suzuki cross-coupling

Protected allylglycine has been hydroborated and the intermediate organoborane employed in Suzuki coupling reactions with a number of olefinic, aromatic and heteroaromatic bromides and iodides to produce a range of novel a-amino acids in good, unoptimised yields. (C) 2000 Elsevier Science Ltd. All rights reserved.