期刊
SCIENCE
卷 289, 期 5485, 页码 1754-1757出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.289.5485.1754
关键词
-
During animal development, cells become progressively more restricted in the cell types to which they can give rise. In the central nervous system (CNS), for example, multipotential stem cells produce various kinds of specified precursors that divide a limited number of times before they terminally differentiate into either neurons OF glial cells. We show here that certain extracellular signals can induce oligodendrocyte precursor cells to revert to multipotential neural stem cells, which can self-renew and give rise to neurons and astrocytes, as well as to oligodendrocytes, Thus, these precursor cells have greater developmental potential than previously thought.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据